What you'll learn

Amino Acids, Peptides, and Protein Architecture

Chemistry

Biochemistry

Organic Chemistry

Peptide Synthesis

Protein Structure and Folding

Peptide Sequencing

Amino Acid Properties and Synthesis

Protein Interactions

 

Requirements

No requirements

 

Description

This course explore the structure, synthesis, and chemistry of these essential building blocks of life. In this comprehensive course, you will explore biomolecules' structure, synthesis, and chemistry.The primary topics covered in this course are:1. Amino Acid Synthesis structure and chemistry: The various methods and mechanisms involved in amino acid synthesis. Learn about the different pathways and reactions required to create these fundamental protein building blocks. Understand the importance of stereochemistry in amino acid synthesis.You will explore the structural features of amino acids, including their backbone, side chains, and functional groups. Gain insight into amino acids' physicochemical properties, such as acidity and basicity. Study the reactivity of amino acids, including their involvement in peptide bond formation and other chemical reactions.2. Peptides and Polypeptides: Investigate the formation and properties of peptides and polypeptides. Understand how amino acids are linked together through peptide bonds to form these chains. Explore the different types of peptides, including dipeptides, tripeptides, and longer polypeptide chains, and how to separate them. Explain the principles behind these techniques and their application in peptide analysis and sequencing.3. Protein Structures: Examine the hierarchical levels of protein structure, including primary, secondary, tertiary, and quaternary structures. Understand how the sequence of amino acids determines the folding and conformation of proteins. Explore the forces and interactions that stabilize protein structures and contribute to their unique functions.By the end of this course, you will have a deep understanding of amino acids, peptides, and protein chemistry. You will be equipped with the knowledge and tools to analyze, synthesize, and comprehend biomolecules. Join us on this exciting journey and unlock the secrets of amino acids, peptides, and proteins!

 

Overview

Section 1: Introduction

 

Lecture 1 Introduction and Overview of Course Topics - Part 1

 

Lecture 2 Introduction and Overview of Course Topics - Part 2

 

Lecture 3 Lect.3_Amino Acids Structures and Conformations

 

Lecture 4 Lect.4_Exercises on R and S

 

Lecture 5 Lect.5_Acid Base Behavior and pI

 

Lecture 6 Lect.6_Exercises on pI and Net Charge

 

Section 2: Amino Acids Synthesis

 

Lecture 7 Synthesis of Amino Acids_Reductive Amination & SN2 reaction

 

Lecture 8 Synthesis of Amino Acids from Alkylation of a Diethyl Malonate Derivative

 

Lecture 9 Synthesis of Amino Acids Using Strecker Synthesis

 

Section 3: Separation of amino acids

 

Lecture 10 Separation of Amino Acids Treatment with Optically Pure Chiral Acid or Base

 

Lecture 11 Separation of Amino Acids Using Enzymatic Resolution

 

Section 4: Peptides and Proteins

 

Lecture 12 Peptide Bond and Peptide Sequencing

 

Lecture 13 Peptide Sequencing

 

Lecture 14 Peptide Synthesis

 

Lecture 15 Automated Peptide Synthesis (Merrifield Method)

 

Section 5: Protein Primary and Secondary Structures

 

Lecture 16 Protein Structure and Interactions

 

Lecture 17 Protein Tertiary Structure and Interactions

 

Lecture 18 Summay and Conclusion

 

 

Biochemistry Students,Students,Chemistry Students,Medicine Student,Pharmacy Students,Undergratue,Collage Students,University Students

Biomolecules_Architecture.part1.rar - 995.0 MB

Biomolecules_Architecture.part2.rar - 205.8 MB