This book presents a detailed account of the theory and methods to tackle systems of strongly interacting particles from a bottom-up approach, which has been largely developed in the past decade by the authors and other experts in the field. This begins with a full characterisation of strongly interacting few-particle systems, which can be dealt with accurately using a variety of analytical and numerical techniques. These non-perturbative solutions can be used to gain qualitative and quantitative insight into more complex problems, especially the many-body problem. The book gives a detailed overview of the relevant and current research literature in the field, and is a valuable tool for researchers and graduate students.Part of IOP Series in Quantum Technology.