The book covers the emerging communication and computational technologies for future cyber-physical systems and discusses the security of in-vehicle communication protocols using automotive embedded systems, presenting an in-depth analysis across various domains, such as manufacturing, transportation, health-care, and smart cities. This book: • Discusses how communication and computing co-design provides dynamic adaptability and centralized control. • Presents the convergence of physical and digital realities within the metaverse and multiverse, setting the stage for the future of cyber-physical-social systems (CPSS). • Presents emerging communication and computational technologies, such as 6G, software-defined networking, cloud computing, blockchain, artificial intelligence, machine learning, virtual reality, and blockchain, for the design and implementation of cyber-physical systems. • Explores advanced topics such as security and privacy in industrial CPS, strategies for protecting serial industrial networks, and enhancing firmware update security in automotive systems. It is primarily written for senior undergraduates, graduate students, and academic researchers in the fields of electrical engineering, electronics and communication engineering, computer science and engineering, and information technology.